96 research outputs found

    04231 Abstracts Collection -- Scheduling in Computer and Manufacturing Systems

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    During 31.05.-04.06.04, the Dagstuhl Seminar 04231 "Scheduling in Computer and Manufacturing Systems" was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available

    Competitive location under proportional choice: 1-suboptimal points on networks

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    This paper is concerned with a competitive or voting location problem on networks under a proportional choice rule that has previously been introduced by Bauer et al. (1993). We refine a discretization result of the authors by proving convexity and concavity properties of related expected payoff functions. Furthermore, we answer the long time open question whether 1-suboptimal points are always vertices by providing a counterexample on a tree network

    Protein alignment algorithms with an efficient backtracking routine on multiple GPUs

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    <p>Abstract</p> <p>Background</p> <p>Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for sequence alignment methods in the nearest future. To overcome this challenge several GPU (Graphics Processing Unit) computing approaches have been proposed lately. These solutions show a great potential of a GPU platform but in most cases address the problem of sequence database scanning and computing only the alignment score whereas the alignment itself is omitted. Thus, the need arose to implement the global and semiglobal Needleman-Wunsch, and Smith-Waterman algorithms with a backtracking procedure which is needed to construct the alignment.</p> <p>Results</p> <p>In this paper we present the solution that performs the alignment of every given sequence pair, which is a required step for progressive multiple sequence alignment methods, as well as for DNA recognition at the DNA assembly stage. Performed tests show that the implementation, with performance up to 6.3 GCUPS on a single GPU for affine gap penalties, is very efficient in comparison to other CPU and GPU-based solutions. Moreover, multiple GPUs support with load balancing makes the application very scalable.</p> <p>Conclusions</p> <p>The article shows that the backtracking procedure of the sequence alignment algorithms may be designed to fit in with the GPU architecture. Therefore, our algorithm, apart from scores, is able to compute pairwise alignments. This opens a wide range of new possibilities, allowing other methods from the area of molecular biology to take advantage of the new computational architecture. Performed tests show that the efficiency of the implementation is excellent. Moreover, the speed of our GPU-based algorithms can be almost linearly increased when using more than one graphics card.</p

    An integrated model for the transshipment yard scheduling problem

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    Future trends in management and operation of assembly systems: from customized assembly systems to cyber-physical systems

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    Future trends in management and operation of assembly systems: from customized assembly systems to cyber-physical systems

    Hybrid adaptive large neighborhood search algorithm for the mixed fleet heterogeneous dial-a-ride problem

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    The mixed fleet heterogeneous dial-a-ride problem (MF-HDARP) consists of designing vehicle routes for a set of users by using a mixed fleet including both heterogeneous conventional and alternative fuel vehicles. In addition, a vehicle is allowed to refuel from a fuel station to eliminate the risk of running out of fuel during its service. We propose an efficient hybrid adaptive large neighborhood search (hybrid ALNS) algorithm for the MF-HDARP. The computational experiments show that the algorithm produces high quality solutions on our generated instances and on HDARP benchmarks instances. Computational experiments also highlight that the newest components added to the standard ALNS algorithm enhance intensification and diversification during the search process

    Good Laboratory Practice for optimization research

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    Good Laboratory Practice has been a part of non-clinical research for over 40 years yet. Optimization Research, despite having many papers discussing standards being published over the same period of time, has yet to embrace standards that underpin its research.In this paper we argue the need to adopt standards in optimization research. Building on previous papers, many of which have suggested that the optimiza- tion research community should adopt certain standards, we suggest a concrete set of recommendations that the community should adopt.We also discuss how the proposals in this paper could be progressed

    Good Laboratory Practice for Optimization Research

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    Good Laboratory Practice has been a part of non-clinical research for over 40 years yet. Optimization Research, despite having many papers discussing standards being published over the same period of time, has yet to embrace standards that underpin its research. In this paper we argue the need to adopt standards in optimization research. Building on previous papers, many of which have suggested that the optimiza- tion research community should adopt certain standards, we suggest a concrete set of recommendations that the community should adopt. We also discuss how the proposals in this paper could be progressed
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